IL1RL1

Across TCGA cell cohorts, IL1RL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,258 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL1RL1-associated GO terms across cancer lineages are Cell-substrate junction organization, Positive regulation of transmission of nerve impulse, and Transposable element silencing by piRNA-mediated heterochromatin formation. Each is linked with IL1RL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both IL1RL1-to-partner and partner-to-IL1RL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction organization grouped by IL1RL1-low versus IL1RL1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RL1→partner) and Y-score (partner→IL1RL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cell-substrate junction organization →	+0.122	+1.037	<.001	<.001	3	7
PANCREAS	Positive regulation of transmission of nerve impulse →	+1.046	+2.737	.005	<.001	3	7
LUNG_NSCLC_LUAD	Transposable element silencing by piRNA-mediated heterochromatin formation →	+0.917	+1.148	.007	.002	3	6
LUNG_NSCLC_LUAD	Cell-substrate junction assembly →	+0.172	+0.936	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Epidermis development →	+0.099	+0.905	<.001	.003	3	6
PANCREAS	Regulation of intracellular transport →	+0.049	+1.559	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,258 associations by consensus.

Cell-substrate junction organization by IL1RL1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →