IL1RL1

Across TCGA cell cohorts, IL1RL1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible IL1RL1-associated genes across cancer lineages are IL36A, OR2T5, and C1orf141. Each is linked with IL1RL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL1RL1-to-partner and partner-to-IL1RL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL36A grouped by IL1RL1-low versus IL1RL1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RL1→partner) and Y-score (partner→IL1RL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	IL36A →	+0.057	+5.169	<.001	.005	3	1
BREAST	OR2T5 →	+0.033	+5.781	<.001	.001	3	1
BREAST	C1orf141 →	+0.049	+5.781	<.001	.001	3	1
BREAST	FOXB2 →	+0.042	+5.169	<.001	.005	3	1
LUNG_NSCLC_LUAD	OBP2B →	+0.049	+4.544	<.001	.003	3	1
SKIN	SCYGR10 →	+0.161	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

IL36A by IL1RL1 expression — BREAST

Explore this box plot interactively →