Across TCGA patient cohorts, IL1RAPL2 mutation is significantly associated with the total protein of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL1RAPL2-associated genes across cancer lineages are MIG-6, Stathmin, and ASNS. Each is linked with IL1RAPL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL1RAPL2-to-partner and partner-to-IL1RAPL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RAPL2→partner) and Y-score (partner→IL1RAPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIG-6 →	+0.143	+2.025	.010	.016	3	2
SKCM	Stathmin →	+0.176	+1.510	.005	.032	3	2
SKCM	ASNS →	+0.340	+1.999	.026	.002	3	2
UCEC	FASN →	+0.264	+2.222	.030	.009	3	2
UCEC	FoxM1 →	+0.214	+1.643	.007	.003	3	2
UCEC	GAPDH →	+0.372	+1.700	.025	.040	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

Exploration

IL1RAPL2 survival (RNA) · tumor vs normal (RNA) · all IL1RAPL2 data types