Across TCGA cell cohorts, IL1RAPL2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible IL1RAPL2-associated genes across cancer lineages are ADAM30, KRTAP4-5, and OR13C3. Each is linked with IL1RAPL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL1RAPL2-to-partner and partner-to-IL1RAPL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RAPL2→partner) and Y-score (partner→IL1RAPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	ADAM30 →	+0.016	+5.029	<.001	.006	3	2
LUNG_SCLC	KRTAP4-5 →	+0.051	+5.029	<.001	.006	3	1
LUNG_SCLC	OR13C3 →	+0.130	+5.643	<.001	.002	3	1
SKIN	MINAR2 →	+0.008	+3.977	<.001	.001	3	1
UPPER_AERODIGESTIVE_TRACT	KCNK16 →	+0.052	+4.736	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

IL1RAPL2 survival (RNA) · tumor vs normal (RNA) · all IL1RAPL2 data types