Across TCGA patient cohorts, IL1RAP protein abundance is significantly associated with the RNA expression of many other genes, with 9,969 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IL1RAP-associated genes across cancer lineages are RN7SKP296, GCNT1P3, and PLAU. Each is linked with IL1RAP in more than 6 cancer types. Because this analysis shows association rather than direction, both IL1RAP-to-partner and partner-to-IL1RAP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RAP→partner) and Y-score (partner→IL1RAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RN7SKP296 →	+1.528	+1.120	<.001	<.001	3	7
GBM	GCNT1P3 →	+1.619	+1.081	<.001	<.001	3	7
LUAD	PLAU →	+1.305	+0.452	<.001	.001	3	6
HNSC	HRH1 →	+0.824	+0.463	<.001	<.001	3	6
HNSC	DUSP6 →	+0.937	+0.428	<.001	<.001	3	6
HNSC	POU2AF1 →	-1.094	-0.411	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,969 associations by consensus.

Exploration

IL1RAP survival (RNA) · tumor vs normal (RNA) · all IL1RAP data types