Across TCGA patient cohorts, IL1RAP mutation is significantly associated with the RNA expression of many other genes, with 4,149 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL1RAP-associated genes across cancer lineages are RN7SL97P, MIR190B, and IGKV3-31. Each is linked with IL1RAP in more than 2 cancer types. Because this analysis shows association rather than direction, both IL1RAP-to-partner and partner-to-IL1RAP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RAP→partner) and Y-score (partner→IL1RAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL97P →	+0.076	+3.155	.002	.008	3	3
CESC	MIR190B →	+0.125	+3.984	<.001	.009	3	3
BRCA	IGKV3-31 →	+0.115	+3.841	<.001	.002	3	2
BRCA	OR10Q2P →	+0.022	+3.841	.001	.002	3	2
LIHC	RNU6-270P →	+0.384	+5.758	<.001	.003	3	2
LIHC	RNU6-1082P →	+0.534	+5.108	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,149 associations by consensus.

Exploration

IL1RAP survival (RNA) · tumor vs normal (RNA) · all IL1RAP data types