IL1R2

Across TCGA patient cohorts, IL1R2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,056 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL1R2-associated proteins across cancer lineages are RBBP6_T984, SNX1_S72, and S100A12. Each is linked with IL1R2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IL1R2-to-partner and partner-to-IL1R2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL1R2 versus RBBP6_T984 in PDAC, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1R2→partner) and Y-score (partner→IL1R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RBBP6_T984 →	-1.431	-0.847	<.001	<.001	3	7
PDAC	SNX1_S72 →	-0.950	-0.991	<.001	<.001	3	7
GBM	S100A12 →	+1.858	+2.138	<.001	<.001	3	7
GBM	S100A9 →	+1.522	+2.191	<.001	<.001	3	7
GBM	SERPINB10 →	+1.153	+1.850	<.001	<.001	3	7
BRCA	ICAM3 →	+0.594	+1.142	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,056 associations by consensus.

IL1R2 vs RBBP6_T984 — PDAC

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