IL1R2

Across TCGA patient cohorts, IL1R2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,566 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL1R2-associated genes across cancer lineages are AMACR, FTLP10, and NDRG1. Each is linked with IL1R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL1R2-to-partner and partner-to-IL1R2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL1R2 versus AMACR in HNSC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1R2→partner) and Y-score (partner→IL1R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AMACR →	-0.562	-0.503	.002	.002	3	2
LSCC	FTLP10 →	+0.627	+0.697	<.001	<.001	3	2
GBM	NDRG1 →	+1.704	+1.241	.004	.009	3	2
GBM	MANSC1 →	-1.007	-1.591	<.001	.008	3	2
GBM	LDHA →	+1.268	+1.232	<.001	.007	3	2
GBM	SLC25A37 →	+0.770	+1.435	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,566 associations by consensus.

IL1R2 vs AMACR — HNSC

Explore this scatter interactively →