IL1R2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IL1R2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,831 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IL1R2-associated GO terms across cancer lineages are Protein transport within lipid bilayer, Cell-cell adhesion mediated by cadherin, and Establishment or maintenance of transmembrane electrochemical gradient. Each is linked with IL1R2 in more than 7 cancer types. Because this analysis shows association rather than direction, both IL1R2-to-partner and partner-to-IL1R2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein transport within lipid bilayer grouped by IL1R2-low versus IL1R2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1R2→partner) and Y-score (partner→IL1R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEProtein transport within lipid bilayer →+0.736+0.618.003.00338
STOMACHCell-cell adhesion mediated by cadherin →+0.145+1.437.002.00238
STOMACHEstablishment or maintenance of transmembrane electrochemical gradient →+0.255+2.486<.001<.00137
BONEPositive regulation of sodium ion transport →+0.214+0.642<.001.00237
PANCREASOpsonization →+1.373+1.566.001<.00137
BLOOD_LymphomaRegulation of T cell apoptotic process →+0.104+2.825<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,831 associations by consensus.

Protein transport within lipid bilayer by IL1R2 expression — BONE

Box plot of Protein transport within lipid bilayer in IL1R2-low vs IL1R2-high samples in BONE.

Explore this box plot interactively →

Exploration