IL1F10

Across TCGA pan-cancer cohorts, IL1F10 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of IL1F10’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where IL1F10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IL1F10 is over-expressed in tumor.

THCA, LUSC, and BRCA are the cancer types where IL1F10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IL1F10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	+0.095	<.001	7	view →
LUSC	Male	All	+0.379	<.001	4	view →
BRCA	All	All	+0.011	.002	4	view →
HNSC	All	All	+0.481	.021	3	view →
PRAD	All	All	+0.076	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

IL1F10–THCA

Open the THCA breakdown →