IL1B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IL1B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,570 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL1B-associated proteins across cancer lineages are ITGAM, MPO, and NCF2. Each is linked with IL1B in more than 9 cancer types. Because this analysis shows association rather than direction, both IL1B-to-partner and partner-to-IL1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL1B versus ITGAM in UCEC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1B→partner) and Y-score (partner→IL1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECITGAM →+0.770+0.922<.001<.001310
GBMMPO →+1.102+0.946<.001.001310
UCECNCF2 →+0.759+1.019<.001<.00139
UCECNCF4 →+0.702+0.997<.001<.00139
GBMPADI4 →+1.179+1.217<.001<.00139
LSCCS100A12 →+1.365+1.206<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,570 associations by consensus.

IL1B vs ITGAM — UCEC

Per-sample scatter of IL1B vs ITGAM in UCEC (Pearson r = 0.48).

Explore this scatter interactively →

Exploration