IL1B

Across TCGA patient cohorts, IL1B protein abundance is significantly associated with the RNA expression of many other genes, with 2,976 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL1B-associated genes across cancer lineages are TREM1, CXCL3, and FPR2. Each is linked with IL1B in more than 2 cancer types. Because this analysis shows association rather than direction, both IL1B-to-partner and partner-to-IL1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL1B versus TREM1 in GBM, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1B→partner) and Y-score (partner→IL1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TREM1 →	+3.179	+2.193	.001	.005	3	3
GBM	CXCL3 →	+3.044	+2.589	.001	.005	3	3
GBM	FPR2 →	+3.372	+2.500	<.001	.006	3	3
HNSC	AQP9 →	+1.018	+1.026	.002	<.001	3	2
GBM	CSF3 →	+3.894	+2.114	.001	.006	3	2
HNSC	PLAUR →	+0.605	+0.764	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,976 associations by consensus.

IL1B vs TREM1 — GBM

Explore this scatter interactively →