IL1A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IL1A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,527 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IL1A-associated proteins across cancer lineages are ITGAM, MMP9, and S100A12. Each is linked with IL1A in more than 9 cancer types. Because this analysis shows association rather than direction, both IL1A-to-partner and partner-to-IL1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL1A versus ITGAM in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1A→partner) and Y-score (partner→IL1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECITGAM →+0.744+1.178<.001<.001310
UCECMMP9 →+1.190+1.215<.001<.00139
HNSCS100A12 →+1.515+1.772<.001<.00139
HNSCPRTN3 →+1.175+1.699<.001<.00139
GBMNCF4 →+0.502+0.577<.001<.00138
PDACAZU1 →+1.006+1.359<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,527 associations by consensus.

IL1A vs ITGAM — UCEC

Per-sample scatter of IL1A vs ITGAM in UCEC (Pearson r = 0.34).

Explore this scatter interactively →

Exploration