IL1A

Across TCGA patient cohorts, IL1A protein abundance is significantly associated with the RNA expression of many other genes, with 2,034 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IL1A-associated genes across cancer lineages are LGALS1, SOX10, and TTC28. Each is linked with IL1A in more than 1 cancer types. Because this analysis shows association rather than direction, both IL1A-to-partner and partner-to-IL1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL1A versus LGALS1 in HNSC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1A→partner) and Y-score (partner→IL1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LGALS1 →	+1.470	+0.945	.001	.002	3	1
HNSC	SOX10 →	-0.537	-1.179	.005	<.001	3	1
HNSC	TTC28 →	-0.955	-1.375	<.001	<.001	3	1
HNSC	CHKB →	-0.654	-1.477	.006	.001	3	1
HNSC	CBX7 →	-0.762	-1.166	<.001	<.001	3	1
HNSC	TNRC6B →	-0.523	-1.152	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,034 associations by consensus.

IL1A vs LGALS1 — HNSC

Explore this scatter interactively →