IL18RAP

Across TCGA patient cohorts, IL18RAP protein abundance is significantly associated with the RNA expression of many other genes, with 1,718 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IL18RAP-associated genes across cancer lineages are SRGAP1, DSC2, and MMRN1. Each is linked with IL18RAP in more than 2 cancer types. Because this analysis shows association rather than direction, both IL18RAP-to-partner and partner-to-IL18RAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL18RAP versus SRGAP1 in BRCA, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL18RAP→partner) and Y-score (partner→IL18RAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SRGAP1 →	+1.146	+0.844	<.001	.003	3	3
UCEC	DSC2 →	+1.501	+0.478	.001	<.001	3	2
LUAD	MMRN1 →	-1.728	-0.825	.006	<.001	3	2
UCEC	MBOAT2 →	+3.377	+0.527	.004	.001	3	2
UCEC	TRAV20 →	-1.262	-0.467	.002	<.001	3	2
UCEC	LINC01612 →	-2.544	-0.530	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,718 associations by consensus.

IL18RAP vs SRGAP1 — BRCA

Explore this scatter interactively →