IL18R1

Across TCGA patient cohorts, IL18R1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,639 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL18R1-associated proteins across cancer lineages are ARHGAP45, WAS, and IL16. Each is linked with IL18R1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IL18R1-to-partner and partner-to-IL18R1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL18R1 versus ARHGAP45 in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL18R1→partner) and Y-score (partner→IL18R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP45 →	+0.601	+0.931	<.001	<.001	3	8
GBM	WAS →	+0.652	+0.979	<.001	<.001	3	8
OV	IL16 →	+0.749	+1.040	<.001	<.001	3	8
GBM	DEF6 →	+0.590	+0.877	<.001	<.001	3	8
GBM	DOCK2 →	+0.585	+0.896	<.001	<.001	3	8
OV	GIMAP7 →	+0.595	+0.739	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,639 associations by consensus.

IL18R1 vs ARHGAP45 — GBM

Explore this scatter interactively →