IL18R1

Across TCGA patient cohorts, IL18R1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,081 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL18R1-associated genes across cancer lineages are TNFSF13B, KMO, and FGL2. Each is linked with IL18R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL18R1-to-partner and partner-to-IL18R1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL18R1 versus TNFSF13B in HNSC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL18R1→partner) and Y-score (partner→IL18R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TNFSF13B →	+1.326	+0.516	<.001	.004	3	2
LSCC	KMO →	+0.581	+0.528	.001	<.001	3	2
HNSC	FGL2 →	+1.351	+0.359	<.001	.009	3	2
HNSC	STAT4 →	+0.941	+0.509	.001	.002	3	2
LSCC	EFNA3 →	-0.895	-0.555	<.001	<.001	3	2
HNSC	IL2RG →	+1.071	+0.511	.005	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,081 associations by consensus.

IL18R1 vs TNFSF13B — HNSC

Explore this scatter interactively →