Across TCGA cell cohorts, IL17REL mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL17REL-associated genes across cancer lineages are CNBD1, OR2B3, and POTEB2. Each is linked with IL17REL in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17REL-to-partner and partner-to-IL17REL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17REL→partner) and Y-score (partner→IL17REL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CNBD1 →	+0.576	+4.977	<.001	.007	3	1
LARGE_INTESTINE	OR2B3 →	+0.022	+5.415	<.001	.004	3	1
LARGE_INTESTINE	POTEB2 →	+0.012	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

IL17REL survival (RNA) · tumor vs normal (RNA) · all IL17REL data types