Across TCGA cell cohorts, IL17REL mutation is significantly associated with the mutation status of many other genes, with 774 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL17REL-associated genes across cancer lineages are FTL, CCDC28A, and MAOB. Each is linked with IL17REL in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17REL-to-partner and partner-to-IL17REL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17REL→partner) and Y-score (partner→IL17REL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FTL →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	CCDC28A →	+3.350	+4.584	.003	.003	1	2
LARGE_INTESTINE	MAOB →	+5.672	+5.672	<.001	<.001	1	2
LARGE_INTESTINE	ZSCAN16 →	+4.087	+5.044	.001	.001	1	2
LARGE_INTESTINE	C18orf63 →	+3.672	+4.799	.002	.002	1	2
LARGE_INTESTINE	CRY1 →	+4.672	+5.329	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 774 associations by consensus.

Exploration

IL17REL survival (RNA) · tumor vs normal (RNA) · all IL17REL data types