IL17RD

Across TCGA patient cohorts, IL17RD mutation is significantly associated with the RNA expression of many other genes, with 3,942 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL17RD-associated genes across cancer lineages are OFD1P16Y, DAOA, and MIR1229. Each is linked with IL17RD in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17RD-to-partner and partner-to-IL17RD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OFD1P16Y grouped by IL17RD-low versus IL17RD-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RD→partner) and Y-score (partner→IL17RD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	OFD1P16Y →	+0.097	+4.305	.004	.007	3	2
LIHC	DAOA →	+0.012	+4.149	<.001	.009	3	2
LIHC	MIR1229 →	+0.358	+3.962	<.001	.003	3	2
LIHC	RNA5SP247 →	+0.368	+3.317	.001	.008	3	2
LIHC	ST13P21 →	+0.027	+3.765	<.001	.004	3	2
LIHC	LINC01075 →	+0.079	+4.149	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,942 associations by consensus.

OFD1P16Y by IL17RD expression — LIHC

Explore this box plot interactively →