IL17RC

Across TCGA cell cohorts, IL17RC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,792 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IL17RC-associated GO terms across cancer lineages are Regulation of macroautophagy, Positive regulation of intracellular transport, and Regulation of cell-substrate junction organization. Each is linked with IL17RC in more than 14 cancer types. Because this analysis shows association rather than direction, both IL17RC-to-partner and partner-to-IL17RC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by IL17RC-low versus IL17RC-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RC→partner) and Y-score (partner→IL17RC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of macroautophagy →	+0.053	+1.388	<.001	<.001	3	15
BONE	Positive regulation of intracellular transport →	+0.069	+1.133	.002	.002	3	14
BONE	Regulation of cell-substrate junction organization →	+0.147	+1.175	<.001	<.001	3	13
CNS	Regulation of intracellular transport →	+0.070	+1.198	<.001	<.001	3	13
SKIN	Vacuolar transport →	+0.050	+0.754	<.001	<.001	3	13
BONE	Endosomal transport →	+0.062	+1.218	.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,792 associations by consensus.

Regulation of macroautophagy by IL17RC expression — BREAST

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