IL17RA

Across TCGA pan-cancer cohorts, IL17RA mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated IL17RA data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IL17RA mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated IL17RA expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC and LUAD are the cancer types where IL17RA mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.933	0.595	.011	17	view →
LUAD	DFS	Median	II,III,IV	0.197	0.717	.005	15	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

IL17RA–HNSC (OS)

Open the HNSC breakdown →