IL17RA

Across TCGA patient cohorts, IL17RA RNA expression is significantly associated with the protein abundance of many other proteins, with 12,579 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL17RA-associated proteins across cancer lineages are APBB1IP, PTPN6, and DEF6. Each is linked with IL17RA in more than 6 cancer types. Because this analysis shows association rather than direction, both IL17RA-to-partner and partner-to-IL17RA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL17RA versus APBB1IP in GBM, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RA→partner) and Y-score (partner→IL17RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	APBB1IP →	+0.715	+0.693	<.001	<.001	3	7
GBM	PTPN6 →	+0.629	+0.508	<.001	<.001	3	6
GBM	DEF6 →	+0.530	+0.546	<.001	<.001	3	5
GBM	FMNL1 →	+0.626	+0.630	<.001	<.001	3	5
UCEC	EVL →	+0.486	+0.381	.001	.002	3	5
GBM	LCP2 →	+0.480	+0.502	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,579 associations by consensus.

IL17RA vs APBB1IP — GBM

Explore this scatter interactively →