IL17RA

Across TCGA patient cohorts, IL17RA protein abundance is significantly associated with the RNA expression of many other genes, with 4,805 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL17RA-associated genes across cancer lineages are RNASEH2B, MEFV, and ZC2HC1A. Each is linked with IL17RA in more than 2 cancer types. Because this analysis shows association rather than direction, both IL17RA-to-partner and partner-to-IL17RA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL17RA versus RNASEH2B in GBM, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RA→partner) and Y-score (partner→IL17RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNASEH2B →	-0.393	-0.310	.001	.005	3	3
LUAD	MEFV →	+0.731	+0.325	<.001	<.001	3	2
HNSC	ZC2HC1A →	-0.729	-0.381	.009	.006	3	2
HNSC	SLC25A36 →	-0.857	-0.305	.001	.003	3	2
HNSC	CEP68 →	-0.546	-0.275	.001	.008	3	2
HNSC	TMEM255A →	-1.146	-0.430	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,805 associations by consensus.

IL17RA vs RNASEH2B — GBM

Explore this scatter interactively →