IL17RA

Across TCGA patient cohorts, IL17RA mutation is significantly associated with the RNA expression of many other genes, with 1,569 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL17RA-associated genes across cancer lineages are RNU4ATAC7P, SFXN1, and THOP1. Each is linked with IL17RA in more than 2 cancer types. Because this analysis shows association rather than direction, both IL17RA-to-partner and partner-to-IL17RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4ATAC7P grouped by IL17RA-low versus IL17RA-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RA→partner) and Y-score (partner→IL17RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU4ATAC7P →	+0.278	+8.055	<.001	.007	3	3
UCEC	SFXN1 →	+0.457	+2.606	.001	.005	3	3
UCEC	THOP1 →	+0.541	+3.743	<.001	<.001	3	3
UCEC	RNF126 →	+0.580	+2.769	<.001	<.001	3	3
CESC	SLC25A5P9 →	+0.055	+5.418	<.001	.005	3	3
LUSC	RN7SL237P →	+0.171	+3.525	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,569 associations by consensus.

RNU4ATAC7P by IL17RA expression — BRCA

Explore this box plot interactively →