IL17RA

Across TCGA cell cohorts, IL17RA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,814 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL17RA-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Endosomal transport. Each is linked with IL17RA in more than 15 cancer types. Because this analysis shows association rather than direction, both IL17RA-to-partner and partner-to-IL17RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by IL17RA-low versus IL17RA-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RA→partner) and Y-score (partner→IL17RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Symbiont-mediated disruption of host cellular anatomical structure →	+0.104	+0.701	.001	<.001	3	16
OVARY	Symbiont-mediated disruption of host anatomical structure →	+0.104	+0.701	.001	<.001	3	16
BREAST	Endosomal transport →	+0.065	+0.943	<.001	<.001	3	15
LUNG_SCLC	Cell division →	+0.064	+0.735	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Regulation of chemokine (C-X-C motif) ligand 1 production →	+1.295	+1.202	.001	<.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of chemokine (C-X-C motif) ligand 1 production →	+1.295	+1.202	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,814 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by IL17RA expression — OVARY

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