IL17D

Across TCGA patient cohorts, IL17D protein abundance is significantly associated with the RNA expression of many other genes, with 766 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL17D-associated genes across cancer lineages are GLRX5, AMELX, and CIB2. Each is linked with IL17D in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17D-to-partner and partner-to-IL17D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL17D versus GLRX5 in HNSC, with a Pearson correlation of -0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17D→partner) and Y-score (partner→IL17D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GLRX5 →	-0.454	-0.766	.008	.007	3	2
HNSC	AMELX →	+0.411	+0.851	.006	.004	3	1
HNSC	CIB2 →	-0.820	-0.983	<.001	<.001	3	1
HNSC	UCK2 →	-0.661	-0.815	.001	.001	3	1
HNSC	NBPF20 →	-0.357	-0.714	.002	.005	3	1
HNSC	THNSL1 →	-0.753	-0.945	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 766 associations by consensus.

IL17D vs GLRX5 — HNSC

Explore this scatter interactively →