IL17B

Across TCGA patient cohorts, IL17B protein abundance is significantly associated with the RNA expression of many other genes, with 13,399 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL17B-associated genes across cancer lineages are BSPRY, H19, and OSBPL2. Each is linked with IL17B in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17B-to-partner and partner-to-IL17B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL17B versus BSPRY in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17B→partner) and Y-score (partner→IL17B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BSPRY →	+1.483	+0.467	<.001	.004	3	1
HNSC	H19 →	-1.498	-0.629	.004	<.001	3	1
HNSC	OSBPL2 →	+0.465	+0.649	.001	.001	3	1
HNSC	C19orf57 →	-0.772	-0.512	.001	.006	3	1
HNSC	MTMR11 →	-0.725	-0.479	.003	.003	3	1
HNSC	BCL6B →	-0.779	-0.543	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,399 associations by consensus.

IL17B vs BSPRY — HNSC

Explore this scatter interactively →