IL17B

Across TCGA cell cohorts, IL17B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,480 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IL17B-associated GO terms across cancer lineages are Cytoplasmic translation, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with IL17B in more than 7 cancer types. Because this analysis shows association rather than direction, both IL17B-to-partner and partner-to-IL17B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by IL17B-low versus IL17B-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17B→partner) and Y-score (partner→IL17B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cytoplasmic translation →	+0.058	+0.383	<.001	<.001	3	8
BLOOD_Leukemia	Negative regulation of syncytium formation by plasma membrane fusion →	+0.054	+0.235	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Regulation of syncytium formation by plasma membrane fusion →	+0.082	+0.175	<.001	.001	3	6
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.056	+0.219	<.001	.001	3	6
LIVER	Keratan sulfate proteoglycan biosynthetic process →	+0.089	+0.438	.001	.007	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.077	+0.118	.009	.006	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,480 associations by consensus.

Cytoplasmic translation by IL17B expression — BLOOD_Leukemia

Explore this box plot interactively →