IL16

Across TCGA patient cohorts, IL16 protein abundance is significantly associated with the RNA expression of many other genes, with 19,476 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL16-associated genes across cancer lineages are CYTH4, APOBEC3H, and GRAP2. Each is linked with IL16 in more than 9 cancer types. Because this analysis shows association rather than direction, both IL16-to-partner and partner-to-IL16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL16 versus CYTH4 in GBM, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL16→partner) and Y-score (partner→IL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.146	+0.751	<.001	<.001	3	10
BRCA	APOBEC3H →	+0.819	+0.528	<.001	<.001	3	10
HNSC	GRAP2 →	+0.902	+0.543	<.001	<.001	3	10
GBM	NCF4 →	+1.258	+0.790	<.001	<.001	3	10
BRCA	IL2RB →	+1.376	+0.654	<.001	<.001	3	10
COAD	GZMH →	+1.476	+0.482	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,476 associations by consensus.

IL16 vs CYTH4 — GBM

Explore this scatter interactively →