IL16

Across TCGA cell cohorts, IL16 mutation is significantly associated with the RNA expression of many other genes, with 372 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL16-associated genes across cancer lineages are C1orf87, RAET1E, and CENPVL1. Each is linked with IL16 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL16-to-partner and partner-to-IL16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf87 grouped by IL16-low versus IL16-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL16→partner) and Y-score (partner→IL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	C1orf87 →	+0.031	+3.716	.002	.005	3	1
BLOOD_Myeloma	RAET1E →	+0.059	+3.662	.001	.005	3	1
BLOOD_Myeloma	CENPVL1 →	+0.009	+3.285	<.001	.009	3	1
CNS	TRPV5 →	+0.025	+4.087	<.001	.004	3	1
CNS	OR2V2 →	+0.027	+4.169	<.001	.008	3	1
CNS	GSC2 →	+0.083	+4.201	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 372 associations by consensus.

C1orf87 by IL16 expression — BLOOD_Myeloma

Explore this box plot interactively →