IL15RA

Across TCGA patient cohorts, IL15RA mutation is significantly associated with the RNA expression of many other genes, with 396 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL15RA-associated genes across cancer lineages are RNU6-634P, HYKK, and TXN2P1. Each is linked with IL15RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL15RA-to-partner and partner-to-IL15RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-634P grouped by IL15RA-low versus IL15RA-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL15RA→partner) and Y-score (partner→IL15RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-634P →	+0.158	+4.408	<.001	.005	3	2
UCEC	HYKK →	+0.441	+3.332	.004	.005	3	2
UCEC	TXN2P1 →	+0.420	+3.769	<.001	.002	3	2
UCEC	MED28P1 →	+0.273	+3.182	.001	.001	3	2
COAD	SNORD114-1 →	+0.925	+4.308	<.001	.009	3	1
COAD	RPL35AP30 →	+0.331	+4.126	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 396 associations by consensus.

RNU6-634P by IL15RA expression — SKCM

Explore this box plot interactively →