IL13RA1

Across TCGA pan-cancer cohorts, IL13RA1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated IL13RA1 data layer compared with 27 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IL13RA1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated IL13RA1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, LUAD, and LSCC are the cancer types where IL13RA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.916	0.300	.020	6	view →
LUAD	DFS	Median	All	0.557	0.748	.035	5	view →
LSCC	DFS	Tertile	II,III,IV	0.200	1.000	.024	5	view →
UCEC	DFS	Tertile	All	1.000	0.697	.016	4	view →
CCRCC	DFS	Median	All	0.281	1.000	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

IL13RA1–HNSC (DFS)

Open the HNSC breakdown →