IL12RB2

Across TCGA patient cohorts, IL12RB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,700 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IL12RB2-associated proteins across cancer lineages are WARS1, GBP1, and GBP5. Each is linked with IL12RB2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IL12RB2-to-partner and partner-to-IL12RB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL12RB2 versus WARS1 in UCEC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL12RB2→partner) and Y-score (partner→IL12RB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WARS1 →	+0.804	+0.761	<.001	.001	3	7
BRCA	GBP1 →	+0.962	+1.255	<.001	<.001	3	7
UCEC	GBP5 →	+1.350	+0.905	<.001	<.001	3	7
UCEC	STAT1 →	+0.743	+0.806	<.001	<.001	3	7
COAD	UBE2L6 →	+0.496	+0.335	<.001	<.001	3	6
HNSC	GZMA →	+1.032	+1.451	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,700 associations by consensus.

IL12RB2 vs WARS1 — UCEC

Explore this scatter interactively →