IL12RB2

Across TCGA cell cohorts, IL12RB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,874 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible IL12RB2-associated GO terms across cancer lineages are Mitochondrial RNA catabolic process, Nucleic acid catabolic process, and Mitochondrial RNA metabolic process. Each is linked with IL12RB2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IL12RB2-to-partner and partner-to-IL12RB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial RNA catabolic process grouped by IL12RB2-low versus IL12RB2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL12RB2→partner) and Y-score (partner→IL12RB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial RNA catabolic process →	+0.093	+0.435	.002	.004	3	7
KIDNEY	Nucleic acid catabolic process →	+0.043	+0.086	.002	.006	3	7
SOFT_TISSUE	Mitochondrial RNA metabolic process →	+0.087	+0.095	<.001	.007	3	6
BONE	RNA catabolic process →	+0.073	+0.721	.002	.005	3	6
BONE	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.120	+0.453	<.001	.002	3	6
CNS	Negative regulation of mRNA metabolic process →	+0.051	+0.226	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,874 associations by consensus.

Mitochondrial RNA catabolic process by IL12RB2 expression — BONE

Explore this box plot interactively →