IL12RB1

Across TCGA patient cohorts, IL12RB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,420 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL12RB1-associated proteins across cancer lineages are PSMB10, PTPN6, and PTPN7. Each is linked with IL12RB1 in more than 9 cancer types. Because this analysis shows association rather than direction, both IL12RB1-to-partner and partner-to-IL12RB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL12RB1 versus PSMB10 in LSCC, with a Pearson correlation of 0.84.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL12RB1→partner) and Y-score (partner→IL12RB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PSMB10 →	+0.655	+0.991	<.001	<.001	3	10
GBM	PTPN6 →	+0.652	+0.668	<.001	<.001	3	10
OV	PTPN7 →	+0.723	+1.061	<.001	<.001	3	10
GBM	PTPRC →	+0.828	+0.758	<.001	<.001	3	10
GBM	RCSD1 →	+0.654	+0.797	<.001	<.001	3	10
LSCC	RCSD1_S351 →	+0.644	+0.779	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,420 associations by consensus.

IL12RB1 vs PSMB10 — LSCC

Explore this scatter interactively →