IL12RB1

Across TCGA patient cohorts, IL12RB1 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,510 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL12RB1-associated proteins across cancer lineages are BAG4, BAG4_S179, and BAP1. Each is linked with IL12RB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL12RB1-to-partner and partner-to-IL12RB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL12RB1 versus BAG4 in LSCC, with a Pearson correlation of 0.54.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL12RB1→partner) and Y-score (partner→IL12RB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BAG4 →	+0.647	+1.192	.001	<.001	3	1
LSCC	BAG4_S179 →	+0.741	+0.799	<.001	<.001	3	1
LSCC	BAP1 →	-0.213	-0.887	<.001	<.001	3	1
LSCC	BNIP1 →	+0.265	+0.920	<.001	<.001	3	1
LSCC	BUD13_S386 →	-0.841	-1.116	<.001	<.001	3	1
LSCC	BUD13_S388 →	-0.531	-0.715	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,510 associations by consensus.

IL12RB1 vs BAG4 — LSCC

Explore this scatter interactively →