IL11RA

Across TCGA patient cohorts, IL11RA protein abundance is significantly associated with the RNA expression of many other genes, with 2,494 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IL11RA-associated genes across cancer lineages are CD99L2, GSR, and ABHD14B. Each is linked with IL11RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL11RA-to-partner and partner-to-IL11RA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL11RA versus CD99L2 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL11RA→partner) and Y-score (partner→IL11RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CD99L2 →	-0.710	-0.586	.001	.002	3	2
HNSC	GSR →	-1.290	-0.938	<.001	.002	3	2
HNSC	ABHD14B →	-1.161	-0.938	.001	.002	3	2
BRCA	NEK4 →	-0.863	-0.885	<.001	<.001	3	2
HNSC	CREB3L4 →	-1.902	-0.938	<.001	.002	3	2
BRCA	AKR7A3 →	-2.905	-1.051	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,494 associations by consensus.

IL11RA vs CD99L2 — BRCA

Explore this scatter interactively →