IL11RA

Across TCGA cell cohorts, IL11RA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,343 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL11RA-associated GO terms across cancer lineages are Nucleic acid catabolic process, Negative regulation of syncytium formation by plasma membrane fusion, and RNA catabolic process. Each is linked with IL11RA in more than 14 cancer types. Because this analysis shows association rather than direction, both IL11RA-to-partner and partner-to-IL11RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleic acid catabolic process grouped by IL11RA-low versus IL11RA-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL11RA→partner) and Y-score (partner→IL11RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Nucleic acid catabolic process →	+0.044	+1.226	.002	.004	2	15
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.158	+1.755	.008	.002	3	14
OVARY	RNA catabolic process →	+0.054	+1.527	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Protein polyglycylation →	+1.074	+1.326	<.001	<.001	3	13
OESOPHAGUS	Regulation of myoblast fusion →	+0.150	+1.755	.006	.002	3	13
OESOPHAGUS	Regulation of macroautophagy →	+0.093	+1.871	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,343 associations by consensus.

Nucleic acid catabolic process by IL11RA expression — STOMACH

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