IL11RA

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IL11RA mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL11RA-associated genes across cancer lineages are RXFP2. Each is linked with IL11RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL11RA-to-partner and partner-to-IL11RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RXFP2 grouped by IL11RA-low versus IL11RA-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL11RA→partner) and Y-score (partner→IL11RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINERXFP2 →+0.032+3.684.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

RXFP2 by IL11RA expression — LARGE_INTESTINE

Box plot of RXFP2 in IL11RA-low vs IL11RA-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration