IL10RB

Across TCGA patient cohorts, IL10RB protein abundance is significantly associated with the RNA expression of many other genes, with 2,796 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL10RB-associated genes across cancer lineages are OGFOD2, RP9P, and KCTD7. Each is linked with IL10RB in more than 1 cancer types. Because this analysis shows association rather than direction, both IL10RB-to-partner and partner-to-IL10RB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL10RB versus OGFOD2 in GBM, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL10RB→partner) and Y-score (partner→IL10RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	OGFOD2 →	-0.287	-0.383	.006	.006	3	2
UCEC	RP9P →	-0.746	-0.343	.004	.006	3	2
GBM	KCTD7 →	-0.476	-0.282	<.001	.003	3	2
PDAC	FGL1 →	-3.220	-0.643	<.001	<.001	3	2
LSCC	GART →	+0.460	+0.225	<.001	.005	3	2
HNSC	UBL5P4 →	+0.739	+0.382	.008	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,796 associations by consensus.

IL10RB vs OGFOD2 — GBM

Explore this scatter interactively →