IL10RB

Across TCGA cell cohorts, IL10RB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,850 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IL10RB-associated GO terms across cancer lineages are Cellular response to type III interferon, Response to type III interferon, and Type III interferon-mediated signaling pathway. Each is linked with IL10RB in more than 18 cancer types. Because this analysis shows association rather than direction, both IL10RB-to-partner and partner-to-IL10RB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to type III interferon grouped by IL10RB-low versus IL10RB-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL10RB→partner) and Y-score (partner→IL10RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cellular response to type III interferon →	+0.317	+1.380	<.001	<.001	3	19
LIVER	Response to type III interferon →	+0.277	+1.254	<.001	<.001	3	19
OESOPHAGUS	Type III interferon-mediated signaling pathway →	+0.317	+1.380	<.001	<.001	3	19
STOMACH	Interleukin-10-mediated signaling pathway →	+0.287	+1.211	<.001	<.001	3	18
STOMACH	Positive regulation of cellular respiration →	+0.183	+0.854	<.001	<.001	3	17
BONE	Positive regulation of protein localization to plasma membrane →	+0.094	+0.946	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,850 associations by consensus.

Cellular response to type III interferon by IL10RB expression — OESOPHAGUS

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