IKZF5

Across TCGA patient cohorts, IKZF5 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,957 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IKZF5-associated proteins across cancer lineages are ERO1A, P4HB, and NHLRC2. Each is linked with IKZF5 in more than 5 cancer types. Because this analysis shows association rather than direction, both IKZF5-to-partner and partner-to-IKZF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IKZF5 versus ERO1A in LUAD, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IKZF5→partner) and Y-score (partner→IKZF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ERO1A →	-0.580	-0.286	<.001	.007	3	6
GBM	P4HB →	-0.561	-0.565	<.001	<.001	3	5
BRCA	NHLRC2 →	+0.280	+0.671	<.001	<.001	3	5
GBM	CALR →	-0.376	-0.492	<.001	.001	3	5
BRCA	CTBP2 →	+0.327	+0.477	<.001	.001	3	5
LSCC	RAD21 →	+0.204	+0.376	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,957 associations by consensus.

IKZF5 vs ERO1A — LUAD

Explore this scatter interactively →