IKZF4

Across TCGA patient cohorts, IKZF4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,278 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IKZF4-associated proteins across cancer lineages are RPL26, RPL7, and SLC2A1. Each is linked with IKZF4 in more than 3 cancer types. Because this analysis shows association rather than direction, both IKZF4-to-partner and partner-to-IKZF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IKZF4 versus RPL26 in OV, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IKZF4→partner) and Y-score (partner→IKZF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RPL26 →	-0.639	-0.885	.002	.001	3	4
GBM	RPL7 →	-0.319	-0.448	.001	<.001	3	4
BRCA	SLC2A1 →	-0.830	-0.471	<.001	<.001	3	4
BRCA	AGO1 →	+0.197	+0.299	<.001	.003	3	4
PDAC	KHDRBS1_S58 →	+0.367	+0.247	<.001	.007	3	4
GBM	SMARCC2 →	+0.355	+0.646	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,278 associations by consensus.

IKZF4 vs RPL26 — OV

Explore this scatter interactively →