Across TCGA patient cohorts, IKZF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,354 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IKZF1-associated proteins across cancer lineages are APOL3, MYO1G, and ARHGAP15. Each is linked with IKZF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both IKZF1-to-partner and partner-to-IKZF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IKZF1→partner) and Y-score (partner→IKZF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	APOL3 →	+0.847	+1.139	<.001	<.001	3	10
LSCC	MYO1G →	+0.615	+1.166	<.001	<.001	3	10
UCEC	ARHGAP15 →	+0.706	+1.071	<.001	<.001	3	10
LSCC	ARHGAP15_S64 →	+1.188	+1.044	<.001	<.001	3	10
OV	ARHGAP25 →	+0.830	+0.985	.001	<.001	3	10
HNSC	ARHGAP30 →	+0.714	+1.358	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,354 associations by consensus.

Exploration

IKZF1 survival (RNA) · tumor vs normal (RNA) · all IKZF1 data types