IKBKGP1

Across TCGA patient cohorts, IKBKGP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,753 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible IKBKGP1-associated GO terms across cancer lineages are Nucleotide-excision repair, Regulation of ubiquitin-dependent protein catabolic process, and Positive regulation of DNA metabolic process. Each is linked with IKBKGP1 in more than 28 cancer types. Because this analysis shows association rather than direction, both IKBKGP1-to-partner and partner-to-IKBKGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide-excision repair grouped by IKBKGP1-low versus IKBKGP1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IKBKGP1→partner) and Y-score (partner→IKBKGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Nucleotide-excision repair →	+0.048	+0.292	<.001	<.001	3	29
DLBC	Regulation of ubiquitin-dependent protein catabolic process →	+0.050	+0.242	<.001	<.001	3	27
DLBC	Positive regulation of DNA metabolic process →	+0.052	+0.274	<.001	<.001	3	27
DLBC	Centrosome duplication →	+0.076	+0.318	.001	<.001	3	27
DLBC	Telomere maintenance via telomere lengthening →	+0.059	+0.258	<.001	<.001	3	27
DLBC	Regulation of DNA recombination →	+0.055	+0.247	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,753 associations by consensus.

Nucleotide-excision repair by IKBKGP1 expression — DLBC

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