IKBKG

Across TCGA pan-cancer cohorts, IKBKG mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated IKBKG data layer compared with 27 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher IKBKG mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated IKBKG expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and GBM are the cancer types where IKBKG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	II,III,IV	0.537	0.231	<.001	46	view →
CCRCC	DFS	Quartile	II,III,IV	1.000	0.812	.020	9	view →
GBM	OS	Median	All	0.443	0.629	.017	4	view →
UCEC	DFS	Median	All	0.936	1.000	.021	2	view →
HNSC	OS	Median	III,IV	1.000	0.946	.037	1	view →
LSCC	DFS	Median	III,IV	1.000	0.867	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

IKBKG–PDAC (OS)

Open the PDAC breakdown →