IKBIP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IKBIP protein abundance is significantly associated with the RNA expression of many other genes, with 19,014 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IKBIP-associated genes across cancer lineages are GFPT2, COL1A1, and LOX. Each is linked with IKBIP in more than 9 cancer types. Because this analysis shows association rather than direction, both IKBIP-to-partner and partner-to-IKBIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IKBIP versus GFPT2 in OV, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IKBIP→partner) and Y-score (partner→IKBIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVGFPT2 →+1.358+0.550<.001<.001310
OVCOL1A1 →+2.760+0.588<.001<.00139
OVLOX →+1.807+0.588<.001<.00139
OVSPARC →+1.925+0.669<.001<.00139
BRCAP3H1 →+0.906+0.540<.001<.00139
OVCOL5A1 →+2.218+0.555<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,014 associations by consensus.

IKBIP vs GFPT2 — OV

Per-sample scatter of IKBIP vs GFPT2 in OV (Pearson r = 0.63).

Explore this scatter interactively →

Exploration