IKBIP

Across TCGA cell cohorts, IKBIP RNA expression is significantly associated with the go_rna of many other GO terms, with 6,035 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IKBIP-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Collagen fibril organization, and Cortisol metabolic process. Each is linked with IKBIP in more than 15 cancer types. Because this analysis shows association rather than direction, both IKBIP-to-partner and partner-to-IKBIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by IKBIP-low versus IKBIP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IKBIP→partner) and Y-score (partner→IKBIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Peptidyl-lysine oxidation →	+1.449	+1.468	<.001	<.001	3	16
BONE	Collagen fibril organization →	+0.343	+1.455	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Cortisol metabolic process →	-1.671	-2.468	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	+0.240	+2.174	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Transport of virus →	+0.281	+2.852	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Intracellular transport of virus →	+0.281	+2.852	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,035 associations by consensus.

Peptidyl-lysine oxidation by IKBIP expression — BONE

Explore this box plot interactively →