IK

Across TCGA patient cohorts, IK RNA expression is significantly associated with the protein abundance of many other proteins, with 13,017 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IK-associated proteins across cancer lineages are HSPA4, PHAX, and DIAPH1. Each is linked with IK in more than 6 cancer types. Because this analysis shows association rather than direction, both IK-to-partner and partner-to-IK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IK versus HSPA4 in LSCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IK→partner) and Y-score (partner→IK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HSPA4 →	+0.322	+0.409	<.001	<.001	3	7
GBM	PHAX →	+0.348	+0.271	<.001	<.001	3	6
OV	DIAPH1 →	+0.618	+0.545	.002	<.001	3	6
BRCA	C5orf24 →	+0.281	+0.341	<.001	<.001	3	6
OV	RAD50 →	+0.428	+0.407	<.001	.001	3	5
LSCC	RRBP1 →	-0.388	-0.303	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,017 associations by consensus.

IK vs HSPA4 — LSCC

Explore this scatter interactively →